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Since the introduction of disposables and gaining popularity of Single-use Technology (SUT) for biopharmaceutical manufacturing there is nevertheless an ongoing controversial discussion on the advantages and disadvantages versus a conventional stainless steel environment. Once the concept for the general operation of the facility in question has been established, the selection and choice of equipment has to be made, their footprint will define the required space, and most likely and preferably they are based on the intended manufacturing process(es) : How much and to what detail is the intended process defined? Which volumes need to be handled? How many tanks / containers of which volume are required?What scale of equipment to choose? This may illustrate that in spite of process economy an...
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